Everything You Need to Know About Tetracycline

Got a prescription for tetracycline and wondering what’s next? You’re not alone. This antibiotic has been around for decades, tackling everything from acne to respiratory infections. Below we break down the basics—how it works, the right way to take it, and the pitfalls to avoid.

What Tetracycline Is Used For

Tetracycline belongs to the broad‑spectrum antibiotic family, meaning it fights a wide range of bacteria. Doctors commonly prescribe it for:

• Acne and other skin infections
• Chlamydia and other sexually transmitted infections
• Respiratory tract infections like bronchitis
• Urinary tract infections
• Travel‑related bacterial illnesses such as typhoid

If your doctor gave you tetracycline, they likely chose it because the infection is known to respond well to this drug.

How to Take It Correctly

Timing matters. Take tetracycline on an empty stomach—usually one hour before or two hours after meals. Food, especially dairy, can bind to the medication and cut its absorption, making it less effective.

Swallow the tablet with a full glass of water and stay upright for at least 30 minutes. This helps prevent irritation of the esophagus, a common complaint with this class of antibiotics.

Typical adult dosing ranges from 250 mg to 500 mg taken two to four times daily, depending on the infection. Always follow the exact schedule your doctor wrote on the prescription label.

If you miss a dose, take it as soon as you remember—unless it’s almost time for the next one. In that case, skip the missed dose; don’t double up.

Common Side Effects to Watch

Most people tolerate tetracycline well, but a few side effects pop up fairly often:

• Nausea or upset stomach
• Diarrhea
• Sun sensitivity—your skin can burn more easily, so wear sunscreen and cover up outdoors
• Discolored teeth in children under eight (this is why doctors avoid it in young kids)

If you notice a rash, swelling, or trouble breathing, stop the medication and seek medical help right away. Those could be signs of a serious allergic reaction.

Important Drug Interactions

Tetracycline doesn’t play well with a few other meds and supplements. Antacids, calcium, iron, and magnesium can all lower its absorption, so space them at least two hours apart.

Blood thinners like warfarin may have their effects amplified, increasing bleeding risk. If you’re on a blood thinner, your doctor might monitor your blood clotting numbers more closely while you’re on tetracycline.

Alcohol isn’t a direct interaction, but heavy drinking can worsen stomach upset and liver strain, making side effects feel worse.

When to Call Your Doctor

Finish the entire prescription, even if you feel better before it’s gone. Stopping early can let bacteria bounce back, leading to a tougher infection.

If symptoms haven’t improved after 3–5 days, or if they get worse, give your doctor a call. You may need a different antibiotic or a longer course.

Pregnant or breastfeeding women should avoid tetracycline unless absolutely necessary—there’s a risk to the baby’s developing teeth and bones.

That’s the quick rundown. Keep these tips handy, stick to the dosing schedule, and watch for any unusual reactions. With the right approach, tetracycline can clear up infections safely and effectively.